500 to 1,000 mg three times daily 3 stars[3 stars]
Taking acetyl-L-carnitine may improve symptoms of diabetic neuropathy.
Alpha Lipoic Acid
600 to 1,200 mg a day 3 stars[3 stars]
Taking alpha lipoic acid may improve insulin sensitivity and help protect against diabetic complications such as nerve damage.
200 to 600 mg daily 3 stars[3 stars]
People with type 2 diabetes tend to have low magnesium levels and supplementing may restore levels and improve glucose control, which in turn may reduce risk of, or slow progression of, diabetes neuropathy.
Refer to label instructions 2 stars[2 stars]
Biotin may improve glucose levels and reduce pain from diabetic nerve damage.
Coenzyme Q10
Refer to label instructions 2 stars[2 stars]
For people with diabetes and neuropathy, the antioxidant coenzyme Q10 may improve nerve function and ease uncomfortable symptoms by 50%.
Vitamin B1 and Vitamin B12
Refer to label instructions 2 stars[2 stars]
Taking vitamin B1 combined with vitamin B12 may improve symptoms of diabetic neuropathy.
Vitamin B1 and Vitamin B6
25 mg vitamin B1 daily, with 50 mg of vitamin B6 daily 2 stars[2 stars]
Taking vitamin B1 combined with vitamin B6 may improve symptoms of diabetic neuropathy.
Vitamin B12
Consult a qualified healthcare practitioner 2 stars[2 stars]
Vitamin B12 is needed for normal nerve cell function, and supplementing with it may improve symptoms of diabetic neuropathy.
Vitamin B6, Vitamin B12, and Folic Acid
Refer to label instructions 2 stars[2 stars]
Taking a supplemental form of folate, vitamin B12, and vitamin B6 may improve neuropathy symptoms and quality of life.
Vitamin D
2,000 IU of vitamin D per day for three months 2 stars[2 stars]
In a preliminary trial, supplementing with vitamin D per day significantly improved pain by almost 50% in patients with diabetic neuropathy.
Vitamin E
900 IU daily 2 stars[2 stars]
Vitamin E supplementation may protect against neuropathy.
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by some in the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

Copyright © 2018 Healthnotes, Inc. All rights reserved.

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The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2018.

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